A21978C, a complex of new acidic peptide antibiotics. Isolation, chemistry, and mass spectral structure elucidation.

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A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation.

A21978C, produced by Streptomyces roseosporus, NRRL 11379, is a complex of new acidic lipopeptolide antibiotics which inhibits Gram-positive bacteria. HPLC separation of the various components from the purified complex resulted in the isolation of A21978C1, -C2 and -C3 (major components) and -C4, -C5, and -C0 (minor components). Each of these components was fermented with cultures of Actinoplan...

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ژورنال

عنوان ژورنال: The Journal of Antibiotics

سال: 1987

ISSN: 0021-8820,1881-1469

DOI: 10.7164/antibiotics.40.761